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Wilfried Dimpfel

Wilfried Dimpfel

Justus Liebig University Giessen, Germany

Title: Enkephalovision, a new computer-operated approach in brain research

Biography

Biography: Wilfried Dimpfel

Abstract

Statement of the Problem: In order to understand brain function several approaches have been used like functional NMRI or quantitative Electroencephalography (qEEG). Functional NMRI suffers from the fact, that it only provides an indirect measurement but covers the whole brain. Quantitative EEG provides a direct measurement of neuronal activity but is limited to the cortical surface. The present approach aimed at achieving higher time resolution in qEEG analysis in order to combine it with eye tracking.

Methodology & Theoretical Orientation: Fast Fourier Transformed EEG signals were subdivided into specially defined frequency ranges now allowing to analyze epoch lengths of 364 ms. Electric power within the frequency ranges was transformed into spectral colors and mixed according to RGB resulting in brain images representing the true measurement not any so-called “false color coding”. Screen capture of the online real time EEG data resulted in the first video-clip. The eye tracker provided a second video as a so-called gaze overlay. By starting the presentation with a gong, offline synchronization using Adobe Premiere software was achieved by taking into account brain and computer dependent processing time.

Findings: Combination of this ultra-fast qEEG analysis with eye tracking allowed functional analysis of brain activity in response to audio-visual challenges with a time resolution of about 3 brain maps per second. Cognitive and emotional challenges revealed particular frequency changes in different brain regions related to individual eye gazes.  The new methodology has been successfully applied in evaluation of TV commercials, web site viewing and efficacy characterization of plant-derived drugs, food supplements and food extracts.

Conclusion & Significance: The combination of ultra-fast qEEG and eye tracking called “EnkephaloVision” for the first time revealed extensive focal electric activity at different brain regions related to momentary focal attention shown by orientation of eye gazes.

Fig. 1

Recent Publications:

  1. Dimpfel W, Hofmann H-C (2014) Neurocode-Tracking Based on Quantitative Fast Dynamic EEG Recording in combination with Eye-Tracking. World Journal of Neuroscience, 4: 106-119. 
  2. Dimpfel W, Chiegoua GN, Gericke N (2016) EnkephaloVision: Anatomical Functionality Indicated by Ultrashort Transient Regional EEG Spectral Power changes during Cognitive and Emotional Challenges. World Journal of Neuroscience, 6: 90-108.
  3. Dimpfel W (2015) Neuromarketing: Neurocode-Tracking in Combination with Eye-Tracking for Quantitative Objective Assessment of TV Commercials. J of Behavioral and Brain Science, 5: 137-147.

4.Dimpfel W, Morys A (2014) Quantitative Objective Assessment of    Websites by Neurocode-Tracking in combination with Eye-Tracking. J of Behavioral and Brain Science 4: 384-395.

5. Dimpfel W, Chiegoua Dipah GN, Suliman S (2016) Proof of Effectiveness of Pascoflair® in Subjects Suffering from Examination Anxiety Using Quantitative EEG in Combination with Eye-Tracking (EnkephaloVision). A Double-Blind, Randomized, Placebo Controlled, 2-Armed, Phase IV Study in Parallel Design. Pharmacology & Pharmacy 7: 424-442.