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John Fox

John Fox

Oxford University, UK

Title: ARTIFICIAL INTELLIGENCE IN MEDICINE: DATA SCIENCE MEETS KNOWLEDGE ENGINEERING

Biography

Biography: John Fox

Abstract

Mathematical methods for supporting clinical decision making have a long history but have not achieved wide adoption because: (1) acquiring the large data sets that are needed to build decision models has been difficult and (2) the perception that mathematical models of decision-making are medically naive. Big data techniques address the problem of acquiring large data sets, but the problem remains that abstract data and algorithms are “black boxes” that are likely to be unintelligible and mistrusted by healthcare professionals and their patients. Artificial Intelligence and knowledge engineering offer many
techniques for clinical decision making and management of care that are complementary to analytic tools and there is good evidence that these methods have practical value and user appeal. The Dentists and OpenClinical approach is based on a naturalistic model of medical expertise formalised in first-order logic (Fox and Das 2000). The Perfume modelling language exploits this approach and the standard syntax and semantics are in the public domain (Sutton and Fox, 2003). Proforma has been used successfully in diverse applications and medical specialties, in some cases at scale and with high impact. Knowledge engineering has much to offer to our ever more pressured health services by increasing the quality and safety of care at reduced
cost, but more is needed to establish the “learning health systems” that are being widely discussed. Combining Proforma with the power of data mining and machine learning may offer a sound foundation for safe and clinically appropriate decision support services and a platform for implementing rapid learning systems in health care. Fox J and Das S, Safe and Sound: Artificial Intelligence in Hazardous Applications, AAAI and MIT Press, 2000. Sutton D and Fox, J “The syntax and semantics of the Proforma guideline modelling language” J Am. Medical Informatics Association, 2003.