Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 7th International Conference on Medical Informatics & Telemedicine Rome, Italy.

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Scientific Program Day 1
Scientific Program Day 2

Day 1 :

Keynote Forum

Ahmad Baghal

University of Arkansas for Medical Sciences, USA

Keynote: Challenges in extracting and curating acute kidney injury data from institutional research enterprise Data Warehouse

Time : 09:30-10:15

Biography:

Ahmad Baghal is faculty in the department of biomedical informatics and director of the Arkansas Clinical Data Repository (AR-CDR) at the University of Arkansas for Medical Sciences (UAMS). He is health informaticist with wealth of skills in healthcare and computer technologies acquired across a wide range of professional roles, postdoctoral fellowships, and graduate education in medicine, computer science, and biomedical Informatics. He led implementation of clinical Enterprise Data Warehouse and accelerated utilization of several medical and public health projects.  

 

Abstract:

The aim of implementing clinical enterprise data warehouse (cEDW) at the University of Arkansas for Medical Sciences (UAMS) was to provide researchers dedicated data source for the conduct of clinical and translational research. Retrospective data analysis has increasingly enhanced breadth and wealth of knowledge of diseases and triggered development of novel treatments to improve patients’ outcomes. Acute Kidney Injury (AKI) is serious medical condition with detrimental health effects, poor outcomes, and high mortality rate. It affects 15% of hospitalized patients and incidence of 1% among the general population. However, little is known about predictors of patients’ outcomes: survival, chronic kidney disease, or death. UAMS, in collaboration with four other medical centers, embarked on a study to identify modifiable factors that lead to poor outcomes among AKI patients. The cohort definition included patients who received renal dialysis, had no diagnosis of end stage renal disease, and had no history of kidney transplant or chronic kidney disease stage 5 at time of first dialysis. Data points including demographics, diagnoses, procedures, comorbidities, laboratory results, and medications, would be extracted from respective medical centres’ cEDW, and, because of the different cEDW implementations between the sites, it was expected data harmonization challenges would be raised. The real challenge was extracting and organizing renal dialysis treatment modalities’, intermittent haemodialysis and continuous renal replacement therapy, data points from each respective centre cEDW’s flow sheets. Not only some centers used paper-based documentation of modalities, but understanding of clinical workflows was critical in producing complete and meaningful data for analysis.

 

Keynote Forum

Ahmed Makki

King Abdulaziz University, Saudi Arabia

Keynote: Integrative medicine & integrated medical education
Biography:

Ahmed Makki works as an Assistant Professor of Surgery at Medical School- Department of Surgery. He works as Examiner of the Royal College of Surgeons in Ireland. I.D. 2121, Examiner of the Royal College of Surgeons of Edinburgh. I.D. 2121, Fellow of the Royal College of Surgeons in Ireland, Fellow of the Royal College of Surgeons of Edinburgh, Fellow of the Royal College of Surgeons of Glasgow and Fellow of the Royal College of Surgeons of England. Ahmed Makki has several credentials like Membership of the Royal College of Physicians & Surgeons of Glasgow, Fellowship of the Royal College of Surgeons in Ireland, Fellowship of the Royal College of Surgeons of Edinburgh, Fellowship of the Royal College of Surgeons of Glasgow and Fellowship of the Royal College of Surgeons of England.

 

Abstract:

In medical practice there is confusion between integrative Medicine and Integrated Medical Education, to eliminate this unintended confusion, we have to define each of them clearly.

 - By Integrative Medicine we mean combination between the western medicine and the complementary alternative medicine, which is based on 5 domains: biologically based approaches, manipulative therapies, mind-body interventions, alternative medicine and energy therapy, while Integrated Medical Education is a planned interdisciplinary unit of medical educational experience.

- The set of medical courses and their contents that students learn under guidance of the university to achieve the graduate competencies, is known as medical curriculum, which has several faces as explicit, implicit, up to extra-curricular set. The medical curriculum structure may take the form of Discrete, Linear, Pyramidal or Spiral structure. Harden in 1984 had suggested that Integration as one of the keys for assessing the degree of innovation in medical curricula through the SPICES strategy, which includes Student cantered learning, Problem based-learning, Integration and Community based with Systemic approach. In 2000, he proposed Harden Ladder which explains the 11 blocks that lead to the integration in medical courses ranging from Isolation up to Multi-, Inter-,Trans-disciplinary approaches.

This entire study illustrates the steps of initiating integrated medical course in details, with illustration of the advantages and disadvantages of integration in medical education. The study also highlights the phases of evaluation and how to improve the existing integrated course via improving content, evaluation methods as well as the outcome of medical education.

 

  • Tele Medicine | Medical Informatics | Digital Health | Bio Medical Informatics | Health Data Analytics Pediatrics Health | Neonatology & Perinatology | Pediatric Neurology & Psychological Disorders | Pediatric Gastroenterology & Hepatology
Location: Foyer

Chair

José Eduardo Fernandes Tavora

Universidade Federal de Minas Gerais, Brazil

Co-Chair

Hoda Dahroug

Egypt ICT Trust Fund, Egypt

Session Introduction

Krystian Kubica

Wroclaw University of Science and Technology, Poland

Title: The importance of bile circulation in cholesterol homeostasis - A three-compartment mathematical model analysis
Biography:

The analysis of the two-compartment model of cholesterol homeostasis has shown a significant influence of the
amount of cholesterol carried by the bile on the total cholesterol concentration in the second compartment,
i.e. peripheral blood. To study the influence of bile circulation on the cholesterol homeostasis, we have developed
a three-compartment model by the addition of a new compartment, describing changes of the bile amount in the
gallbladder. Now our model allows to consider: Chole-sterol synthesis in the liver, cholesterol exchange kinetics
between compartments, the rate of cholesterol entry and loss with bile, the loss of cholesterol due to the conversion
into cholic acid, cholesterol consumption by tissues, dietary cholesterol, gallbladder filling and emptying rates and
gallbladder bile accumulation ability. Our model consists of three equations (ODE) and fourteen parameters. All
parameters in our model can be divided into five groups:
1. Parameters whose values result directly from physiological knowledge: The tissues demand for cholesterol,
volume of blood serum in the liver and in the blood stream, total amount of bile, loss of cholesterol with feces,
time of gallbladder filling and emptying.
2. Parameters whose values result indirectly from physiological knowledge through equations describing particular
processes. This group includes: Parameter describing the rate of cholesterol synthesis, parameters responsible
for the rate of cholic acid synthesis and the medium rate of cholic acid flow from the liver into the gallbladder.
3. Parameters which are bound together by postulated equations to describe known physiological changes.
4. Parameters estimated on the basis of a case study.
5. Parameters which could be described as effective rate constants responsible for multistep processes of cholesterol
exchange between two compartments: Blood in the liver and peripheral blood.
The model allows us to perform the analysis with different gallbladder physiological conditions, i.e. differences in
bile accumulation, patency of the bile ducts and gallbladder motility. Based on the obtained results we speculate that
inter-individual features regulating the bile circulation might result in different responses to the dietary cholesterol
(hypo- and hyper responders).The analysis of the two-compartment model of cholesterol homeostasis has shown a significant influence of the
amount of cholesterol carried by the bile on the total cholesterol concentration in the second compartment,
i.e. peripheral blood. To study the influence of bile circulation on the cholesterol homeostasis, we have developed
a three-compartment model by the addition of a new compartment, describing changes of the bile amount in the
gallbladder. Now our model allows to consider: Chole-sterol synthesis in the liver, cholesterol exchange kinetics
between compartments, the rate of cholesterol entry and loss with bile, the loss of cholesterol due to the conversion
into cholic acid, cholesterol consumption by tissues, dietary cholesterol, gallbladder filling and emptying rates and
gallbladder bile accumulation ability. Our model consists of three equations (ODE) and fourteen parameters. All
parameters in our model can be divided into five groups:
1. Parameters whose values result directly from physiological knowledge: The tissues demand for cholesterol,
volume of blood serum in the liver and in the blood stream, total amount of bile, loss of cholesterol with feces,
time of gallbladder filling and emptying.
2. Parameters whose values result indirectly from physiological knowledge through equations describing particular
processes. This group includes: Parameter describing the rate of cholesterol synthesis, parameters responsible
for the rate of cholic acid synthesis and the medium rate of cholic acid flow from the liver into the gallbladder.
3. Parameters which are bound together by postulated equations to describe known physiological changes.
4. Parameters estimated on the basis of a case study.
5. Parameters which could be described as effective rate constants responsible for multistep processes of cholesterol
exchange between two compartments: Blood in the liver and peripheral blood.
The model allows us to perform the analysis with different gallbladder physiological conditions, i.e. differences in
bile accumulation, patency of the bile ducts and gallbladder motility. Based on the obtained results we speculate that
inter-individual features regulating the bile circulation might result in different responses to the dietary cholesterol
(hypo- and hyper responders).

Abstract:

Krystian Kubica is Biochemist and Physicist, Head of the Computer Simulation team of Biological Systems at the Department of Biomedical Engineering,
Wroclaw University of Technology. Research interests: Biophysics of biological membranes (lipid phase behaviour, interaction between biologically active
compounds and membranes, the influence of molecular probes on membrane properties, the influence of lipid oxidation on membrane properties, membrane
electroporation, physiological process modelling cholesterol homeostasis, molecular mechanism of thermoregulation, bone remodelling, pharmacokinetic). He
has published 37 research papers. He is also the author of 7 patents. He has an experience in:
• Theoretical and experimental studies on biological membranes.
• Theoretical modeling of biological systems.
• Biochemical techniques of isolation, separation and characterization of biological compounds.